The building block of life, the biological cell, is an entity of astonishing coherency; billions of chemical processes take place within it every second – metabolism, molecular transport, gene expression, DNA replication, extracellular communication, reproduction, cell differentiation just to name a few. There are 50 trillion cells in the human body and their combined DNA unraveled would cover the distance from the Earth to the Sun well over 400 times! All of this cooperates beautifully to maintain a living breathing organism adapted for interaction with an exterior universe of innumerable physical processes. it is interesting to note that the DNA spiral is composed of 64 codons, precisely matching the 64 tetrahedron crystalline geometry of hyperspace.
In short, there is a preeminent problem with modern physics, namely us – Life. Everything works pretty fine with current models but the presence of life poses a significant challenge to them. However, a unified theory of physics should be able to explain universal processes, from the microscopic to the macroscopic, including life, consciousness and everything it entails. Until such a theory exists, we really cannot claim to know what kind of cosmological phenomena we really are. Our vision of ourselves is still incomplete. The notion of a universe moving towards ever increasing disorder is disproven by our very existence; the living, breathing human body is a system of incomprehensible interconnectivity, intertwined with the universe at the very quantum level, and, as we shall see, the underlying matrix making this organization possible is the very space in which it exists
2017 – Ever since Francis Crick and James Watson determined the primary structure of DNA to be a double helix, scientists have wondered how DNA is further organized to allow its entire length to pack into the nucleus such that the cell’s copying machinery can access it at different points in the cell’s cycle of activity. https://www.sciencedaily.com/releases/2017/07/170727141510.htm
‘Beyond the cell’ exists microbes and yet the level of inbuilt intelligence staggers a rational mind, perhaps the most pertinent question is if so much intelligence underpins the bio functions essential for all life, where did the directive come from that strikes ‘the balance’ for co-existence originate? surely, even a fool can see the prerequisites for life are guided, every orchestra requires a conductor if cacophonous melee’s are to be avoided, life is ”no exception” to this essential guiding rule of ”mind”. Maccy –
For consideration; Human cells are massively larger and more complex than bacteria and yet microbes keep up relentless intelligent warfare. surprisingly sophisticated, multi level attacks by microbes using protein molecules and micro RNA against plants and animals.
”These complex assaults can directly manipulate genes to produce unique proteins. These altered proteins change normal functions to produce new types of activity helpful to the microbe”.
eg, The eukaryote cell is very organized into compartments. These discrete regions of the cell have specific functions. Microbes manipulate the organelle’s unique functions to gain advantage over the cell.
Some microbes go after the larger 3D structure of the DNA in the nucleus. Recent research (see previous post on genetic new genetic complexity) has shown that regulation of DNA is fantastically complex and now includes three-dimensional structures that hold the DNA in various positions inside the nucleus. (Manipulation of this structure by microbes is an entirely new field called patho-epigenetics.) Somehow, microbes understand much more than we do about how DNA is regulated. First the effector protein from the microbe has to get to the nucleus through special tags that take the molecule in through the very complex nuclear pore mechanism.
To specifically attack the fundamental organelles of the cell, microbes use extremely sophisticated techniques that involve multiple levels of DNA codes, manipulation of histone codes, an understanding of how proteins are folded, and how newly produced versions of these proteins will interact in vastly complex pathways and cascades in human cells. They, also, build incredibly complex secretion weapons to send these molecules to particular places in the cell. Much of this is extremely difficult for humans to decipher and is currently unknown.
How do small microbes, a thousandth the size of a human cell, understand how to do this? Meanwhile, our cells must understand the extremely varied attacks of a large number of different microbes and counteract them.
How can anyone not see the intelligent behavior in these microbes and in our cells?
Essential reading – http://jonlieffmd.com/blog/intelligent-microbes-attack-organelles